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Home > Health Information > Health E-News > Women's Health 

Too Much Coffee May Weaken Bones

Older women who drink several cups of coffee a day may be putting their health at risk, claim the authors of a recently published study. The study, published in the American Journal of Clinical Nutrition, links high coffee consumption, those who drink more than three or four cups a day, to an increased risk of bone loss. 

Previous studies have left many researchers baffled, as results regarding caffeine and bone loss have been conflicting. Some researchers have said that caffeine is connected with increasing the risk of hip fractures as well as poor calcium retention. Others such as the National Institutes of Health Osteoporosis and Related Bone Diseases National Resource Center (NIH ORBD~NRC) disagree stating that the two are not related if the woman has an adequate intake of calcium. 

What makes this study unique is the fact that it focuses not just on caffeine and bone loss but also the impact caffeine may have on women with a certain genetic makeup. The results of this recent study may spur more discussion regarding what impact caffeine may actually have on post-menopausal women. 

The Study

The study, which was done over a three-year period, involved nearly 100 women whose average age was 71. The participants included both heavy and light coffee drinkers enabling the researchers to compare the bone mineral densities of both groups of women. 

The researchers also analyzed any possible link to osteoporosis as well as any impact caffeine may have on the vitamin D receptor gene. Present in some women, this receptor gene, called “tt,” affects the body’s ability to absorb vitamin D. Vitamin D, like calcium, is necessary for healthy bones. Most people do not know if they carry the tt genotype unless they have undergone extensive genetic testing. 

In addition, the researchers also noted the participants’ alcohol consumption, smoking history, dietary intake, and use of vitamins and/or mineral supplements. The participants did not take any calcium or vitamin D supplements at the time of the study. 

In order to determine bone loss and the vitamin D absorption rate of the participants, the researchers took blood and urine samples as well as scans of the hip, spine, and three other sites at the beginning of the study, at six-month intervals, and then again at the end of the study. 

The women were divided into two groups according to their caffeine consumption. Those who consumed less than 300 milligrams of caffeine per day were considered part of the low-caffeine group while those who consumed more than 300 milligrams were in the high-caffeine group. 

According to the National Coffee Association, a US trade organization, an eight-ounce cup of brewed coffee contains anywhere from 65 to 120 milligrams of caffeine, with the average amount being 85 milligrams. The broad range, explains the trade association, is due to a number of factors that affect how much caffeine a cup of coffee contains - factors such as the variety of coffee bean, where it was grown, how it was processed, and how the coffee was brewed.  

Study Results

At the end of the study, the researchers discovered that the women in the high-caffeine category who carried the tt genotype lost more bone over time than the other participants, including those with the same tt genotype but who were in the low-caffeine category. The bone loss was especially significant in the spine area. 

The researchers also noted a higher rate of bone loss in the spine among those who consumed high levels of coffee in comparison to those who drank less, regardless of whether the individual carried the tt genotype. 

They conclude that in post-menopausal elderly women, high levels of caffeine does have an effect on bone loss, especially if the woman carries the tt genotype.

Always consult your physician for more information.


What is osteoporosis? 
Osteoporosis is a progressive condition in which bone density is lost, thereby weakening the bones and making them more susceptible to fractures.

Who is affected by osteoporosis?
Osteoporosis is very prevalent in the US. It affects over 10 million individuals, with women four times more likely to develop osteoporosis than men. Estrogen deficiency is one significant cause of accelerated bone loss in women during and after menopause.

Other risk factors for osteoporosis
Although the exact medical cause for osteoporosis is unknown, a number of factors contribute to osteoporosis, including the following:

  • aging
    Bones become less dense and weaker with age.
  • race
    Caucasian and Asian women are most at risk, although all races may develop the disease.
  • body weight and bone structure
    People who weigh less and have small body frames are more at risk for developing osteoporosis.
  • lifestyle factors
    The following lifestyle factors may increase a person's risk of osteoporosis:
    • physical inactivity
    • caffeine
    • excessive alcohol use
    • smoking
    • dietary calcium and vitamin D deficiency
  • certain medications
  • family history of bone disease

What are the symptoms of osteoporosis?
Persons with osteoporosis may not develop any symptoms, or may have pain in their bones and muscles, particularly in their back. The symptoms of osteoporosis may resemble other bone disorders or medical problems. Always consult your physician for a diagnosis.

How osteoporosis is diagnosed
In addition to a complete medical history and physical examination, diagnostic procedures for osteoporosis may include the following:

  • family medical history
  • x-rays (skeletal) - a diagnostic test that uses invisible electromagnetic energy beams to produce images of internal tissues, bones, and organs onto film.
  • bone density test (Also called bone densitometry.) - measurement of the mass of bone in relation to its volume to determine the risk of developing osteoporosis.
  • blood tests (to measure serum calcium and potassium levels)

The effects of this disease can best be managed with early diagnosis and treatment.

Treatment for osteoporosis
Specific treatment for osteoporosis will be determined by your physician based on:

  • your age, overall health, and medical history
  • extent of the disease
  • your tolerance for specific medications, procedures, or therapies
  • expectations for the course of the disease
  • your opinion or preference

The goals of managing osteoporosis are to decrease pain, prevent fractures, and minimize further bone loss. Some of the methods used to treat osteoporosis are also the methods to help prevent it from developing, including the following:

  • Maintain an appropriate body weight.
  • Increase walking and other weight-bearing exercises.
  • Minimize caffeine and alcohol consumption.
  • Stop smoking.
  • Maintain an adequate intake of calcium through diet and supplements. Vitamin D is also necessary because it facilitates the absorption of calcium.
  • Prevent falls in the elderly to prevent fractures (e.g., install hand railings or assistive devices in the bathroom, shower, etc.).
  • Consult your physician regarding a medication regimen.

Always consult your physician for more information.

November 2002

The Study

Study Results

What is osteoporosis? 

Who is affected by osteoporosis?

Other risk factors for osteoporosis

What are the symptoms of osteoporosis?

How osteoporosis is diagnosed

Treatment for osteoporosis

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Online Resources:

American Journal of Clinical Nutrition

National Coffee Association

National Institutes of Health Osteoporosis and Related Bone Diseases National Resource Center (NIH ORBD~NRC)

 

 

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